Sutezolid / Oxazolidinone
Chemical class: Oxazolidinone
Background
Sutezolid is in the same class of drugs as linezolid (oxazolidinones), which is used in some countries as a treatment option for drug-resistant TB (DR-TB). Tests conducted over the past decade have indicated that sutezolid may have a better therapeutic potential than linezolid.
Additional Resources:
Research:
- Press Release: TB Alliance Sublicenses Promising Anti-Tuberculosis Drug from the Medicines Patent Pool
- Press Release: PAN-TB Collaboration to Advance Investigational Tuberculosis Drug Regimens to Phase 2 Clinical Trials
TB Alliance is committed to making sutezolid data and drug material available to the research community. For more information, please visit:
- Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects | Antimicrob Agents Chemother
- Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis | Antimicrob Agents Chemother
- Sterilizing Activities of Novel Combinations Lacking First- and Second-Line Drugs in a Murine Model of Tuberculosis | Antimicrob Agents Chemother
- Global tuberculosis drug development pipeline: the need and the reality | Lancet
Phase 2
Partners
- Bill & Melinda Gates Medical Research Institute
