TB must be treated with multiple drugs to achieve maximal efficacy and prevent resistance. To transform treatment, novel TB regimens are needed. TB Alliance aims to register new drugs in combination with one another, or with existing TB drugs. The following regimens have been or currently are the subject of TB Alliance clinical trials.
Ongoing Clinical Development
Bedaquiline + Pretomanid + Linezolid
Bedaquiline + Pretomanid + Moxifloxacin + Pyrazinamide
Isoniazid + Rifampin + Pyrazinamide + Ethambutol