TBI-223
Background:
Oxazolidinones are mainly used as antimicrobials. The antibacterial effect of oxazolidinones occurs by working as protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. Oxazolidinones have shown activity against M. tb and several are either in development for, or already used, to treat TB. Linezolid, sutezolid, and delpazolid are all members of the oxazolidinone class.
Stage of Development:
Phase 2

Trial Regimens
This trial has the following regimens: