Compound

TBI-223 / Oxazolidinone

Chemical Class: Oxazolidinone

Our Pipeline

TBI-223 / Oxazolidinone

Oxazolidinone

Background:

Oxazolidinones are mainly used as antimicrobials. The antibacterial effect of oxazolidinones is by working as protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome.

Oxazolidinones have shown activity against M.tb and several are either in development for, or already used to treat TB. Linezolid, Sutezolid, and Cycloserine are all members of the oxazolidinone class.

Additional Resources:

Stage of Development:

Phase 1

Trial Associations

This compound has appeared in the following trials:

Trial Associations

This compound has appeared in the following trials

Partners

This compound is developed with the following partners: