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Protocol for a phase 2, partially-blinded, randomised trial assessing the safety and efficacy of sorfequiline or bedaquiline, in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009)
Publication: Research Square (preprint)
Effectiveness and safety of the BPaL regimen in the Philippines
Publication: Journal of Clinical Tuberculosis and Other Mycobacterial Diseases
In vitro pharmacokinetics and pharmacodynamics of the diarylquinoline TBAJ-587 and its metabolites against Mycobacterium tuberculosis
Publication: bioRxiv
Children, caregivers and health workers’ perceptions and experiences of the XTEMP-R tool to improve tuberculosis treatment
Publication: PLOS Global Public Health
Population pharmacokinetics of TBAJ-587 and its mainmetabolites—Evaluation of different loading dose strategiesand early dose selection
Publication: British Journal of Clinical Pharmacology
An economic analysis of BPaL for multidrug-resistant TB in South Africa and the Philippines
Publication: IJTLD OPEN
ACTG A5409 (RAD-TB): Study protocol for a phase 2 randomized, adaptive, dose-ranging, open-label trial of novel regimens for the treatment of pulmonary tuberculosis
Publication: BMC Trials
Hepatic safety of pretomanid- and pyrazinamide-containing regimens in TB Alliance clinical trials
Publication: IJTLD Open
A Novel Approach to Evaluating the Design of Pediatric Pharmacokinetic Studies Focused on Accurate Dose Selection
Publication: Clinical Pharmacokinetics