TBA-7371

TBA-7371

Background:

The enzyme DprE1 is involved in the synthesis of arabinans which are an essential part of mycobacterial cell walls. This is a new target and these inhibitors are active against M. tb strains resistant to known TB drugs. TBA-7371 has demonstrated in vivo efficacy and a thus far acceptable safety profile.

Stage of Development:

Phase 2

Trial Compounds

This trial has the following compounds:

Trial Regimens

This trial has the following regimens: