TBA-7371
Partners:
Background:
The enzyme DprE1 is involved in the synthesis of arabinans which are an essential part of mycobacterial cell walls. This is a new target and these inhibitors are active against M. tb strains resistant to known TB drugs. TBA-7371 has demonstrated in vivo efficacy and a thus far acceptable safety profile.
Stage of Development:
Phase 2
Trial Regimens
This trial has the following regimens: