Research Papers

This database includes peer-reviewed publications authored or funded by TB Alliance. Use the tags on the right to filter by subject, or search for a particular author or term using the search bar.

Displaying 132 papers

Turning the tide on tuberculosis: a combined effort

7/2007 - Spigleman M. Turning the tide on tuberculosis: a combined effort. SciDevNet. 2007 4 Jul. http://www.scidev.net/global/health/opinion/turning-the-tide-on-tuberculosis-a-combined-effor.html. Accessed March 11, 2016

Mycobacterium tuberculosis DNA gyrase as a target for drug discovery

6/2007 - Mdluli K, Ma Z. Mycobacterium tuberculosis DNA gyrase as a target for drug discovery. Infect Disord Drug Targets. 2007 Jun;7(2):159-68. http://www.ingentaconnect.com/content/ben/iddt/2007/00000007/00000002/art00008?token=00521b85a26b1174e1f7b76504c48662a2

Tags: Drug Discovery, Drug Targets, M.tb. Biology, MDR-TB, Preclinical Data

Challenges associated with current and future TB treatment

6/2007 - Laurenzi M, Ginsberg AM, Spigelman M. Challenges associated with current and future TB treatment. Infect Disord Drug Targets. 2007 Jun;7(2):105-19. http://www.ingentaconnect.com/content/ben/iddt/2007/00000007/00000002/art00004?token=004e1567d370e7e442f206

Author(s): Laurenzi, M., A. Ginsberg, and M. Spigelman

Tags: Advocacy, Clinical Development, Editorials, Global Pipeline, Trial Design

Planning to improve global health: the next decade of tuberculosis control

5/2007 - Dermot Maher, Chris Dye, Katherine Floyd, et. al. Planning to improve global health: the next decade of tuberculosis control. Bull World Health Organ. 2007 May; 85(5): 341–347. doi: 10.2471/06.037820

Tags: Advocacy, Editorials, MDR-TB, Policy, TB Burden, TB-HIV

Challenges in tuberculosis drug research and development

3/2007 - Ginsberg AM, Spigelman M. Challenges in tuberculosis drug research and development. Nat Med. 2007 Mar;13(3):290-4. http://www.nature.com/nm/journal/v13/n3/full/nm0307-290.html. Accessed March 7, 2016

Tags: Clinical Development, Editorials, Global Pipeline, Trial Design

Antimycobacterium Agents

1/2007 - Ma Z, Ginsberg A, Spigelman M. Antimycobacterium Agents. Elsevier, Philadelphia, PA. 2007 Jan; 700-4, 719-20, 26.

Tags: Clinical Development, Drug Discovery, Drug Targets, Global Pipeline, M.tb. Biology, MDR-TB, Moxifloxacin, Preclinical Models, Pretomanid/PA-824, Pyrazinamide, Rifapentine, TB-HIV, Trial Design

Novel targets for tuberculosis drug discovery

10/2006 - Mdluli K, Spigelman M. Novel targets for tuberculosis drug discovery. Curr Opin Pharmacol. 2006 Oct;6(5):459-67. http://www.sciencedirect.com/science/article/pii/S1471489206001354. Accessed March 7, 2016

Tags: Drug Discovery, Drug Targets, M.tb. Biology

Tuberculosis drug development pipeline: progress and hope

3/2006 - Spigelman M, Gillespie S. Tuberculosis drug development pipeline: progress and hope. Lancet. 2006 Mar 18;367(9514):945-7. http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(06)68388-8/abstract. Accessed March 7, 2016

Tags: Advocacy, Clinical Development, Drug Discovery, Editorials, Global Pipeline

Opportunities for overcoming tuberculosis: new treatment regimens

1/2006 - Freire MC. Opportunities for overcoming tuberculosis: new treatment regimens. World Hosp Health Serv. 2006;42(1):34-7. http://www.ncbi.nlm.nih.gov/pubmed/16669375. Accessed March 7, 2016

Tags: Advocacy, Clinical Development, Editorials, Global Pipeline, Policy, Trial Design

New drugs for tuberculosis: current status and future prospects

6/2005 - O'Brien RJ, Spigelman M. New drugs for tuberculosis: current status and future prospects. Clin Chest Med. 2005 Jun;26(2):327-40, vii. http://www.sciencedirect.com/science/article/pii/S0272523105000158. Accessed March 7, 2016

Tags: Clinical Development, Drug Discovery, Editorials, Global Pipeline, Moxifloxacin, Pretomanid/PA-824, Rifapentine

Mycobacterium tuberculosis: new tricks for an old bug

8/2004 - Spigelman M, Ma Z. Mycobacterium tuberculosis: new tricks for an old bug. Expert Rev Anti Infect Ther. 2004 Aug;2(4):467-9.https://www.researchgate.net/publication/8234528_Mycobacterium_tuberculosis_New_tricks_for_an_old_bug. Accessed March 7, 2016

Tags: Advocacy, Drug Discovery, Drug Targets, Editorials, Global Pipeline, Pharmacokinetics

Joining forces to develop weapons against TB: together we must.

1/2002 - Freire M, Roscigno G. Joining forces to develop weapons against TB: together we must. Bull World Health Organ. 2002;80(6):429. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567524/pdf/12131997.pdf. Accessed March 7, 2016

Tags: Advocacy, Editorials, MDR-TB, Moxifloxacin, Pretomanid/PA-824, TB-HIV

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