Malate Synthetase Inhibitors

Our Pipeline

Malate Synthetase Inhibitors

Background:

Malate synthase (GlcB) is essential for M. tb to survive in-host and to establish chronic infection. Studies on one of the subseries of the inhibitors are ongoing to improve potency and the absorption, distribution, metabolism, and excretion (ADME) properties.

Stage of Development:

Lead Identification

Trial Associations

This compound has appeared in the following trials: