Delivering treatments for TB.
We envision a world where no one dies of tuberculosis. We are dedicated to the discovery, development, and delivery of better, faster-acting, and affordable cures to help end the TB pandemic.
Current treatments for highly drug-resistant forms of TB have taken 18 months or longer
People can take an average of 14,000 pills over the course of treatment
With poor outcomes, as the WHO reports only a 59% success rate for all people with drug-resistant TB
Now there are new options.
Novel regimens can shorten treatment and help reduce the treatment burden for people with highly drug-resistant forms of TB.
For example, patients can now access a
3-drug, all-oral, six month regimen
Fewer than 750 pills over the course of treatment
Approximately 90% success rate
The future of TB R&D.
We’re working hard to transform treatment for everyone with TB—to be able to treat all forms of TB faster and more effectively.
In 3 months or less
We believe the compounds are already in our pipeline to make this happen, if we can marshal funding, investments, and political will.
Looking ahead, we’re exploring the area of immunotherapy, with a goal to make TB treatment as short as 7-10 days. This uses the body’s immune system along with effective regimens to fight off infection.
References 1. The Review on Antimicrobial Resistance. Tackling Drug-Resistant Infections Globally. Available at: www.amr-review.org 2. WHO (2021). Global TB Report 2021. Available at:https://www.who.int/publications/i/item/9789240037021 3. Conradie F, et al. Bedaquiline, pretomanid and linezolid for treatment of extensively drug resistant, intolerant or non-responsive multidrug resistant pulmonary tuberculosis. N Eng J Med 2020;382:893-902.