Research Papers

Global adoption of 6-month drug-resistant TB regimens: Projected uptake by 2026

Publication: PLOS One

Author(s): A Gupta, S Juneja, V Babawale, N R Majidovich, N Ndjeka, P T M Nguyen, P Nargiza Nusratovna, D R Omanito, T T Pakasi, Y Terleeva, A Toktogonova, Y Waheed, Z Myint, Z Yanlin, S Sahu

1/2024

Tags: Advocacy, Bedaquiline (TMC-207), BPaL, Linezolid, Moxifloxacin, Policy, Pretomanid/PA-824, TB Burden, TB Drug Market, TB Market

YES, WE HAVE the POWER to END TB!

Publication: Indian Journal of Tuberculosis

Author(s): Nibedita Rath, Chaitali Nikam, Stephanie Seidel, Anindya Sinha, Vijay Arora

6/2023

Tags: Advocacy, Community Engagement, TB Burden, Underserved Populations

Stable compounded bedaquiline suspensions to support practical implementation of pediatric dosing in the field

Publication: International Journal of Tuberculosis and Lung Disease

Author(s): R Taneja, M C Nahata, J Scarim, P G Pande, A Scarim, G Hoddinott, C L Fourie, R K Jew, H S Schaaf, A J Garcia-Prats, A C Hesseling

3/2023

Tags: Bedaquiline (TMC-207), BENEFIT Kids, Childhood TB, TB Burden, TB Market, Underserved Populations

Lifesaving, cost-saving: Innovative simplified regimens for drug-resistant tuberculosis

Publication: PLOS Global Public Health

Author(s): Aastha Gupta, Sandeep Juneja, Suvanand Sahu, Mohammed Yassin, Grania Brigden, Eliud Wandwalo, Saurabh Rane, Fuad Mirzayev, Matteo Zignol

11/2022

Tags: Bedaquiline (TMC-207), BPaL, Linezolid, Pretomanid/PA-824, TB Burden, TB Drug Market, TB Market

Tuberculosis and antimicrobial resistance - new models of research and development needed

Publication: Bulletin of the World Health Organization

Author(s): Brigden G, Castro JL, Ditiu L, Gray G, Hanna D, Low M, Matsoso MP, Perry G, Spigelman M, Swaminathan S, Torreele E, Wong S

5/2017

Tags: MDR-TB, TB Burden, XDR-TB

Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fl uoroquinolones: results from a multicountry surveillance project

Publication: Zignol, Matteo, Anna Dean, and Natavan Alikhanova. "Population-based Resistance of Mycobacterium Tuberculosis." The Lancet (Published Online July 7, 2016 Http://dx.doi.org/10.1016/S1473-3099(16)30190-6):

7/2016

Tags: Drug-Sensitivity Testing, MDR-TB, Moxifloxacin, Pyrazinamide, TB Burden

Global burden of drug-resistant tuberculosis in children: a mathematical modelling study

Publication: Peter J Dodd, Charalambos Sismanidis, James A Seddon. Global burden of drug-resistant tuberculosis in children: a mathematical modelling study. The Lancet Infectious Diseases , Volume 0 , Issue 0

6/2016

Tags: Childhood TB, MDR-TB, TB Burden, XDR-TB

"Understanding and addressing the tuberculosis case detection gap national inventory studies to improve estimates of incidence and strengthen surveillance" with comments

Publication: Sismanidis C, Glaziou P, Bloss E, et. al. "Understanding and addressing the tuberculosis case detection gap national inventory studies to improve estimates of incidence and strengthen surveillance" with comments. 2016 Mar

3/2016

Tags: Advocacy, Editorials, MDR-TB, Policy, TB Burden, TB Drug Market, TB Market

Grand Convergence: Aligning Technologies & Realities in Global Health

Publication: Yamey G, Morel C. Investing in Health Innovation: A Cornerstone to Achieving Global Health Convergence. PLOS Biology. 2016 Mar 1;14(3). doi: 10.1371/journal.pbio.1002389.

3/2016

Tags: Advocacy, Editorials, Policy, TB Burden

Investing in Health Innovation: A Cornerstone to Achieving Global Health Convergence

Publication: Yamey G, Morel C. Investing in Health Innovation: A Cornerstone to Achieving Global Health Convergence. PLOS Biology. 2016 Mar 1;14(3). doi: 10.1371/journal.pbio.1002389.

3/2016

Tags: Advocacy, Editorials, Policy, TB Burden

Understanding and addressing the tuberculosis case detection gap national inventory studies to improve estimates of incidence and strengthen surveillance

Publication: Sismanidis C, Glaziou P, Bloss E, et. al. Understanding and addressing the tuberculosis case detection gap national inventory studies to improve estimates of incidence and strengthen surveillance. 2016 Mar.

3/2016

Tags: Advocacy, Editorials, MDR-TB, Policy, TB Burden, TB Drug Market, TB Market

The procurement landscape of pediatric tuberculosis treatment: a Global Drug Facility perspective

Publication: Scott C, Gardiner E, de Lucia A. The procurement landscape of pediatric tuberculosis treatment: a Global Drug Facility perspective. Int J Tuberc Lung Dis. 2015 Dec;19 Suppl 1:17-22. doi: 10.5588/ijtld.15.0478.

12/2015

Tags: Advocacy, Childhood TB, Policy, Regimen Change, TB Burden, TB Drug Market, TB Market

Burden of childhood tuberculosis in 22 high-burden countries, a mathematical modelling study

Publication: Dodd PJ, Gardiner E, Coghlan R, Seddon JA. Burden of childhood tuberculosis in 22 high-burden countries: a mathematical modelling study. Lancet Glob Health. 2014 Aug;2(8):e453-9. doi: 10.1016/S2214-109X(14)70245-1.

7/2014

Tags: Childhood TB, TB Burden, TB Market

Drugs for neglected diseases: part II

Publication: Kaneko T. Drugs for neglected diseases: part II. Future Med Chem. 2011 Sep;3(11):1329-30. doi: 10.4155/fmc.11.104.

9/2011

Tags: Advocacy, Clinical Development, Drug Discovery, Editorials, Global Pipeline, TB Burden

Drug repositioning in the treatment of malaria and TB

Publication: Nzila A, Ma Z, Chibale K. Drug repositioning in the treatment of malaria and TB. Future Med Chem. 2011 Sep;3(11):1413-26. doi: 10.4155/fmc.11.95.

Author(s): Alexis Nzil, Zhenkun Ma, Kelly Chibale

9/2011

Tags: Advocacy, Editorials, MDR-TB, TB Burden, XDR-TB

Drugs for neglected diseases: part I

Publication: Kaneko T. Drugs for neglected diseases: part I. Future Med Chem. 2011 Aug;3(10):1235-7. doi: 10.4155/fmc.11.103.

8/2011

Tags: Advocacy, Clinical Development, Drug Discovery, Editorials, Global Pipeline, TB Burden, TB-HIV

Size and Usage Patterns of Private TB Drug Markets in the High Burden Countries

Publication: Wells WA, Ge CF, Patel N, Oh T, Gardiner E, Kimerling ME. Size and usage patterns of private TB drug markets in the high burden countries. PLoS One. 2011 May 4;6(5):e18964. doi: 10.1371/journal.pone.0018964.

5/2011

Tags: Policy, TB Burden, TB Drug Market, TB Market

Drugs in development for tuberculosis

Publication: Ginsberg AM, Drugs in development for tuberculosis. Drugs. 2010 Dec 3;70(17):2201-14. doi: 10.2165/11538170-000000000-00000.

12/2010

Tags: Advocacy, Bedaquiline (TMC-207), Clinical Development, Editorials, Global Pipeline, Pretomanid/PA-824, Rifapentine, TB Burden

Viewpoint: Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infection

Publication: Zumla A, Atun R, Maeurer M, et; al. Viewpoint: Scientific dogmas, paradoxes and mysteries of latent Mycobacterium tuberculosis infection. Trop Med Int Health. 2010 Nov 2; doi: 10.1111/j.1365-3156.2010.02665.x

11/2010

Tags: Advocacy, Editorials, TB Burden

Estimating the market for tuberculosis drugs in industrialized and developing nations

Publication: Schwalbe NR, Wells WA, Geaneotes AP, et. al. Estimating the market for tuberculosis drugs in industrialized and developing nations. Int J Tuberc Lung Dis. 2008 Oct;12(10):1173-81. http://www.ingentaconnect.com/content/iuatld/ijtld/2008/00000012/00000010/a

10/2008

Tags: Regimen Change, TB Burden, TB Drug Market, TB Market